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Search for "neurotrophic effect" in Full Text gives 2 result(s) in Beilstein Journal of Organic Chemistry.
Terpenoids from Glechoma hederacea var. longituba and their biological activities
Beilstein J. Org. Chem. 2022, 18, 555–566, doi:10.3762/bjoc.18.58
- ) cell line. Keywords: antineuroinflammation; cytotoxicity; Glechoma hederacea var. longituba; neurotrophic effect; terpenoid; Introduction Glechoma hederacea var. longituba is a perennial plant in the family Labiatae. It is commonly known as ‘ground ivy’ and ‘gill over the ground’ and is widely
- of an 80% MeOH extract of G. hederacea var. longituba. The structures of these compounds were established by 1D and 2D NMR and HRESIMS, comparison of experimental and calculated ECD data, and hydrolysis. All isolated compounds were evaluated for antineuroinflammatory activity, neurotrophic effect
- , and cytotoxicity. Compounds 2 and 5–7 caused significantly reduced NO levels. Compound 5 exhibited a neurotrophic effect. Interestingly, compounds 4 and 5 showed differences in antineuroinflammatory activity and neurotrophic effect according to the C-2' functional group of the glucopyranosyl group
Chemical constituents of Chaenomeles sinensis twigs and their biological activity
Beilstein J. Org. Chem. 2020, 16, 3078–3085, doi:10.3762/bjoc.16.257
- effects including cytotoxicity against cancer cell lines, antineuroinflammatory activity, and potential neurotrophic effect were evaluated. Keywords: antineuroinflammation; Chaenomeles sinensis; cytotoxicity; megastigmane; neurotrophic effect; Introduction Chaenomeles sinensis (Thouin) Koehne (Rosaceae
- viability (54.9 ± 2.8%). The other phytochemicals displayed mild or no NO inhibitory effects (IC50 > 50 μM). Also, the potential neurotrophic effect of the isolated compounds 1–12 was evaluated by assessing their induction levels of nerve growth factor (NGF) secretion in C6 cells (Table 4). Among the tested
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